"Laodice" (mid-third century BCE): Seleucid princess, wife of king Mithridates II of Pontus.
- Father: Antiochus II Theos
- Mother: Laodice I
- Husband: Mithridates II of Pontus
- Children: Laodice III; another Laodice
- In 245, Laodice I and her son Seleucus II Callinicus were involved in the Laodicean War (or Third Syrian War). To gain support from Mithridates II of Pontus, he was given a woman in marriage, whose name is not known. As a marriage gift, Phrygia was transferred as well.
- This woman and Mithidates had at least two daughters named Laodice; hence, it has been assumed that the Seleucid princess who was their mother, was also called Laodice.