Cleopatra VI Tryphaena (c.95- after 55): queen of the Ptolemaic Empire.
- Father: Ptolemy IX Soter
- Mother: an Egyptian lady
- Husband: Ptolemy XII Auletes
- Daughter: Berenice IV
- c.95 Born
- 80/79: Marries to her brother Ptolemy XII Auletes, who has unexpectedly become king
- 76: Birth of Berenice IV
- 69/68: Cleopatra VI Tryphaena disappears from our records
- 58: Ptolemy XII is expelled from Egypt; Cleopatra VI and her daughter Berenice IV rule the country
- 57: End of the co-rule; Berenice is sole ruler of Egypt
- Cleopatra may have tried to speed up her husband's return
- 56/55: The Roman governor in Syria, Aulus Gabinius, bribed by Ptolemy XII, agrees to support Ptolemy, who is in Alexandria in March 55; a Roman military unit supports the king. Berenice is executed in July.
- Cleopatra VI again disappears from our sources; she must have died before her husband, who was succeeded in 51 by Cleopatra VII