Ptolemy IV Philopator: king of the Ptolemaic Empire, ruled from 222 to 204.
- Father: Ptolemy III Euergetes
- Mother: Berenice II
- Wife: his sister Arsinoe III
- Son: Ptolemy V Epiphanes
- 245 or 244: Born
- Already as a young man, he is called Philopator, "the man who loves his father"
- Succeeds his father between 5 and 16 February 222; many relatives are killed (including his mother) by his ministers Agathocles and Sosibius
- 221: First skirmishes of the Fourth Syrian War: Antiochus III the Great attacks the Ptolemaic possessions in Syria
- 220: Ptolemy marries his sister Arsinoe III
- 219: Antiochus reconquers Seleucia (the port of Antioch, which had been conquered by Ptolemy III in the Third Syrian War) and proceeds to the south
- 13 June 217: Ptolemy's army defeats the Seleucid army at Raphia with an army that consists partly of native Egyptian soldiers
- October 217: Peace is concluded; the Seleucid Empire keeps Seleucia. In Egypt, the victory is attributed to Isis and Serapis.
- Revolts in Egypt; the Nubians conquer the Dodecaschoenus.
- 9 October 210: Birth of Ptolemy V
- October/November: Revolt of Horwennefer / Ankhwennefer
- 29 November 205: Ptolemy V is made co-ruler
- July or August 204: Death; Arsinoe is assassinated
Egyptian title: Iwaennetjerwymenkhwy Setepptah Userkara Sekhemankhamun; andkhdjet meryese ("Son of the divine benefactors, Chosen by Ptah, Mighty Ka of Ra, Living power of Amun; may he live forever, beloved of Isis"; the benefactors are Ptolemy III Euergetes and Berenice)
Succeeded by: Ptolemy V Epiphanes