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Bruttia Crispina (†193 CE): name of a Roman empress, wife of the emperor Commodus.
- daughter of Gaius Bruttius Praesens, a former consul
- daughter of Laberia Marcia Hostilia Crispina Moecia Cornelia
- a brother Lucius Brutius Quintius Crispinus
- Date of birth not recorded
- Summer 178: Marries to Commodus
- 180: Second consulship of Gaius Bruttius Praesens; death of Marcus Aurelius; accession of Commodus
- 181 Conspiracy of Lucilla
- 182: Possible pregnancy
- 187: Consulship of her brother Lucius Bruttius Quintius Crispinus
- 192: Accused of adultery, she is exiled to Capri
- 192, 31 December: Commodus killed
- 193 Crispina is murdered; damnatio memoriae
The Historia Augusta and Cassius Dio suggest that Commodus exiled his wife after the conspiracy of Lucilla,note[Historia Augusta, Commodus 5.9 and Cassius Dio, Roman History 72.4.6.] but several inscriptions prove that she was still in favor.note[CIL 8.16530 (Theveste, 185); CIL 3.12487 (Neatarnarea, 187); CIL 8.22689 (Sabratha, 192).]